[HTML][HTML] Treatment of COVID-19 with conestat alfa, a regulator of the complement, contact activation and kallikrein-kinin system

P Urwyler, S Moser, P Charitos, IAFM Heijnen… - Frontiers in …, 2020 - frontiersin.org
A dysregulated immune response with hyperinflammation is observed in patients with
severe coronavirus disease 2019 (COVID-19). The aim of the present study was to assess …

Effect of trospium chloride on urodynamic parameters in patients with detrusor hyperreflexia due to spinal cord injuries: a multicentre placebo-controlled double-blind …

M Stöhrer, P Bauer, BM Giannetti, R Richter… - Urologia …, 1991 - karger.com
In a multicentre placebo-controlled double-blind study 61 patients with spinal cord injuries
and detrusor hyperreflexia were treated: 20 mg trospium chloride was given twice daily over …

Recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-oedema: a phase 2, multicentre, randomised, double-blind, placebo-controlled …

MA Riedl, V Grivcheva-Panovska, D Moldovan, J Baker… - The Lancet, 2017 - thelancet.com
Background Hereditary angio-oedema is a recurrent, oedematous disorder caused by
deficiency of functional C1 inhibitor. Infusions of plasma-derived C1 esterase inhibitor deter …

A randomized, controlled, double-blind, multi-center trial to evaluate the efficacy and safety of a liquid containing ivy leaves dry extract (EA 575®) vs. placebo in the …

A Schaefer, MS Kehr, BM Giannetti… - Die Pharmazie-An …, 2016 - ingentaconnect.com
This randomized, placebo-controlled, double-blind trial was conducted to assess the efficacy
and safety of ivy leaves cough liquid in the treatment of acute cough. A total of 181 adult …

Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled …

BM Giannetti, C Staiger, M Bulitta… - British journal of sports …, 2010 - bjsm.bmj.com
Objective The objective was to show the superiority of comfrey root extract ointment to
placebo ointment in patients with acute upper or lower back pain. Design The study was …

Antibiotics from basidiomycetes: XIV. Isolation and biological characterization of hypnophilin, pleurotellol, and pleurotellic acid from Pleurotellus hypnophilus (Berk.) …

J Kupka, T Anke, BM Giannetti, W Steglich - Archives of microbiology, 1981 - Springer
Three new antibiotically active metabolites were isolated from cultures of the fungus
Pleurotellus hypnophilus. The structures which are closely related to the coriolins were …

Schizonellin A and B, new glycolipids from Schizonella melanogramma

G Deml, T Anke, F Oberwinkler, BM Giannetti… - Phytochemistry, 1980 - Elsevier
Two new glycolipids, schizonellin A and B, were isolated from cultures of the smut fungus
Schizonella melanogramma. Their structures were elucidated by chemical degradation and …

ANTIBIOTICS FROM BASIDIOMYCETES. XIII THE ALLIACOLS A AND B FROM MARASMIUS ALLIACEUS (JACQ. ex FR.) FR.

T Anke, WH Watson, BM Giannetti… - The Journal of …, 1981 - jstage.jst.go.jp
Two antimicrobial and cytotoxic metabolites were isolated from fermentation broth of
Marasmius alliaceus. The structures of the two crystalline antibiotics, alliacols A (6) and B (1) …

Integrated effects of the vasodilating beta-blocker nebivolol on exercise performance, energy metabolism, cardiovascular and neurohormonal parameters in physically …

HG Predel, W Mainka, W Schillings, H Knigge… - Journal of human …, 2001 - nature.com
Objective: The present study was designed to investigate the integrated effects of the beta-1-
selective blocker with vasodilator properties, nebivolol, on systemic haemodynamics …

[PDF][PDF] How dextran sulfate affects C1-inhibitor activity: a model for polysaccharide potentiation

M Dijk, J Holkers, P Voskamp, BM Giannetti… - Structure, 2016 - cell.com
C1-inhibitor is a key inhibitor of the complement and contact activation systems, and
mutations in the protein can cause hereditary angioedema. Through an unknown …