Background Alcohol use is a leading risk factor for death and disability, but its overall
association with health remains complex given the possible protective effects of moderate …

A hallmark of cancer is reactivation/alteration of pathways that control cellular differentiation
during developmental processes. Evidence indicates that WNT, Notch, BMP and Hedgehog …

Abstract Background and Aims The alcohol harm paradox (AHP) posits that disadvantaged
groups suffer from higher rates of alcohol‐related harm compared with advantaged groups …

Background Rigorous analysis of levels and trends in exposure to leading risk factors and
quantification of their effect on human health are important to identify where public health is …

Background Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in
this paper) are a major cause of morbidity and mortality globally, although the burden and …

Background Accurate and up-to-date assessment of demographic metrics is crucial for
understanding a wide range of social, economic, and public health issues that affect …

Gravitational waves were discovered with the detection of binary black-hole mergers and
they should also be detectable from lower-mass neutron-star mergers. These are predicted …

The decrease of acetylcholine receptors at neuromuscular junctions of myasthenic patients
has been attributed to an antibody-mediated autoimmune process that accelerates receptor …

Background Several countries are considering a minimum price policy for alcohol, but
concerns exist about the potential effects on drinkers with low incomes. We aimed to assess …

We present the first cosmological parameter constraints using measurements of type Ia
supernovae (SNe Ia) from the Dark Energy Survey Supernova Program (DES-SN). The …