Disseminated cancer cells rely on intricate interactions among diverse cell types in the tumor-
associated stroma, vasculature, and immune system for survival and growth. Ubiquitous …

Abstract c-Jun N-terminal kinase (JNK) is activated by diverse cell stimuli, including stress,
growth factors, and cytokines. Traditionally, activation of JNK by stress treatment is thought …

Insulin‐like growth factor (IGF)‐I protects many cell types from apoptosis. As a result, it is
possible that IGF‐I‐responsive cancer cells may be resistant to apoptosis‐inducing …

Ataxia-telangiectasia mutated (ATM) protein kinase regulates the DNA damage response
(DDR) and is associated with cancer suppression. Here we report a cancer-promoting role …

Immunotherapy has emerged as a promising approach to treat cancer. However, partial
responses across multiple clinical trials support the significance of characterizing intertumor …

Objectives: Sport injury is the leading cause of hospitalization in Canadian youth and
represents a high burden to the health care system. This study aims to describe the …

Tumors are much stiffer than healthy tissue, and progressively stiffen as the cancer
develops. Tumor stiffening is largely the result of extracellular matrix (ECM) remodeling, for …

Objective To evaluate the effectiveness of a junior high school-based sports injury
prevention programme to reduce injuries through neuromuscular training (NMT). Methods …

The heterogeneity and aggressiveness of triple-negative breast cancer (TNBC) contribute to
its early recurrence and metastasis. Despite substantial research to identify effective …

The primary aim of this report was to examine the significance of increased DNA sequence
copy number (gene amplification) in human prostate cancers. Three methodologies …