User profiles for "author:Christian Gluud"
 | Christian GluudThe Copenhagen Trial Unit, Centre for Clinical Intervention Research Verified email at ctu.dk Cited by 69320 |
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
G Bjelakovic, D Nikolova, LL Gluud, RG Simonetti… - Jama, 2007 - jamanetwork.com
Context Antioxidant supplements are used for prevention of several diseases. Objective To
assess the effect of antioxidant supplements on mortality in randomized primary and …
assess the effect of antioxidant supplements on mortality in randomized primary and …
Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
G Bjelakovic, D Nikolova, LL Gluud… - Cochrane database …, 2012 - cochranelibrary.com
Antioxidant supplements for prevention of mortality in healthy participants and patients with
various diseases - Bjelakovic, G - 2012 | Cochrane Library Skip to Content Cookies Our site …
various diseases - Bjelakovic, G - 2012 | Cochrane Library Skip to Content Cookies Our site …
Vitamin D supplementation for prevention of mortality in adults
G Bjelakovic, LL Gluud, D Nikolova… - Cochrane database …, 2014 - cochranelibrary.com
Background Available evidence on the effects of vitamin D on mortality has been
inconclusive. In a recent systematic review, we found evidence that vitamin D 3 may …
inconclusive. In a recent systematic review, we found evidence that vitamin D 3 may …
[HTML][HTML] When and how should multiple imputation be used for handling missing data in randomised clinical trials–a practical guide with flowcharts
Background Missing data may seriously compromise inferences from randomised clinical
trials, especially if missing data are not handled appropriately. The potential bias due to …
trials, especially if missing data are not handled appropriately. The potential bias due to …
Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study
Objective To examine whether the association of inadequate or unclear allocation
concealment and lack of blinding with biased estimates of intervention effects varies with the …
concealment and lack of blinding with biased estimates of intervention effects varies with the …
Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses
LL Kjaergard, J Villumsen, C Gluud - Annals of internal medicine, 2001 - acpjournals.org
Purpose: To explore whether reported methodologic quality affects estimated intervention
effects in randomized trials and contributes to discrepancies between the results of large …
effects in randomized trials and contributes to discrepancies between the results of large …
Trial sequential analysis may establish when firm evidence is reached in cumulative meta-analysis
BACKGROUND AND OBJECTIVE: Cumulative meta-analyses are prone to produce
spurious P< 0.05 because of repeated testing of significance as trial data accumulate …
spurious P< 0.05 because of repeated testing of significance as trial data accumulate …
[HTML][HTML] Trial sequential analysis in systematic reviews with meta-analysis
Background Most meta-analyses in systematic reviews, including Cochrane ones, do not
have sufficient statistical power to detect or refute even large intervention effects. This is why …
have sufficient statistical power to detect or refute even large intervention effects. This is why …
Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials
Published evidence suggests that aspects of trial design lead to biased intervention effect
estimates, but findings from different studies are inconsistent. This study combined data from …
estimates, but findings from different studies are inconsistent. This study combined data from …
Trial sequential analysis reveals insufficient information size and potentially false positive results in many meta-analyses
OBJECTIVES: To evaluate meta-analyses with trial sequential analysis (TSA). TSA adjusts
for random error risk and provides the required number of participants (information size) in a …
for random error risk and provides the required number of participants (information size) in a …