Abstract Cancer survivors constitute 3.5% of the United States population, but second
primary malignancies among this high-risk group now account for 16% of all cancer …

Although a number of risk factors have been identified for breast cancer, mechanisms by
which they increase risk of the disease are not clear. Breast cancer etiology could, in part, be …

Abstract Disparities exist between African-American and European-American women in the
incidence and nature of breast cancer. African-American women are more often diagnosed …

Background Population-based estimates of the risk of breast cancer associated with
germline pathogenic variants in cancer-predisposition genes are critically needed for risk …

Introduction The aim of this study was to describe breast tumor subtypes by common breast
cancer risk factors and to determine correlates of subtypes using baseline data from two …

Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of
African ancestry compared to women of European ancestry. In search of common risk alleles …

Oxidative stress, resulting from the imbalance between prooxidant and antioxidant states,
damages DNA, proteins, cell membranes, and mitochondria and seems to play a role in …

Recombination, together with mutation, gives rise to genetic variation in populations. Here
we leverage the recent mixture of people of African and European ancestry in the Americas …

AG to C polymorphism (rs2910164) is located within the sequence of miR-146a precursor,
which leads to a change from a G: U pair to a C: U mismatch in its stem region. The …

Most common breast cancer susceptibility variants have been identified through genome-
wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …