Cancer survivorship—genetic susceptibility and second primary cancers: research strategies and recommendations
LB Travis, CS Rabkin, LM Brown… - Journal of the …, 2006 - academic.oup.com
Abstract Cancer survivors constitute 3.5% of the United States population, but second
primary malignancies among this high-risk group now account for 16% of all cancer …
primary malignancies among this high-risk group now account for 16% of all cancer …
Oxidants and antioxidants in breast cancer
CB Ambrosone - Antioxidants & redox signaling, 2000 - liebertpub.com
Although a number of risk factors have been identified for breast cancer, mechanisms by
which they increase risk of the disease are not clear. Breast cancer etiology could, in part, be …
which they increase risk of the disease are not clear. Breast cancer etiology could, in part, be …
Breast cancer in African-American women: differences in tumor biology from European-American women
K Amend, D Hicks, CB Ambrosone - Cancer research, 2006 - AACR
Abstract Disparities exist between African-American and European-American women in the
incidence and nature of breast cancer. African-American women are more often diagnosed …
incidence and nature of breast cancer. African-American women are more often diagnosed …
[HTML][HTML] A population-based study of genes previously implicated in breast cancer
C Hu, SN Hart, R Gnanaolivu, H Huang… - … England Journal of …, 2021 - Mass Medical Soc
Background Population-based estimates of the risk of breast cancer associated with
germline pathogenic variants in cancer-predisposition genes are critically needed for risk …
germline pathogenic variants in cancer-predisposition genes are critically needed for risk …
[HTML][HTML] Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors
Introduction The aim of this study was to describe breast tumor subtypes by common breast
cancer risk factors and to determine correlates of subtypes using baseline data from two …
cancer risk factors and to determine correlates of subtypes using baseline data from two …
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer
Estrogen receptor (ER)-negative breast cancer shows a higher incidence in women of
African ancestry compared to women of European ancestry. In search of common risk alleles …
African ancestry compared to women of European ancestry. In search of common risk alleles …
Manganese Superoxide Dismutase (MnSOD) Genetic Polymorphisms, Dietary Antioxidants, and Risk of Breast Cancer
Oxidative stress, resulting from the imbalance between prooxidant and antioxidant states,
damages DNA, proteins, cell membranes, and mitochondria and seems to play a role in …
damages DNA, proteins, cell membranes, and mitochondria and seems to play a role in …
The landscape of recombination in African Americans
Recombination, together with mutation, gives rise to genetic variation in populations. Here
we leverage the recent mixture of people of African and European ancestry in the Americas …
we leverage the recent mixture of people of African and European ancestry in the Americas …
A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis
J Shen, CB Ambrosone, RA DiCioccio… - …, 2008 - academic.oup.com
AG to C polymorphism (rs2910164) is located within the sequence of miR-146a precursor,
which leads to a change from a G: U pair to a C: U mismatch in its stem region. The …
which leads to a change from a G: U pair to a C: U mismatch in its stem region. The …
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
RL Milne, KB Kuchenbaecker, K Michailidou… - Nature …, 2017 - nature.com
Most common breast cancer susceptibility variants have been identified through genome-
wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …
wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease …