The diagnosis and management of food allergy and food intolerances

JL Turnbull, HN Adams… - Alimentary pharmacology & …, 2015 - Wiley Online Library
Background Adverse reactions to food include immune mediated food allergies and non‐
immune mediated food intolerances. Food allergies and intolerances are often confused by …

Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome

DA Gorard, GW Libby… - Alimentary pharmacology …, 1994 - Wiley Online Library
Background: Antidepressants are used in the treatment of irritable bowel syndrome but it is
unclear whether any symptomatic improvement is due solely to correction of an associated …

Intestinal transit in anxiety and depression.

DA Gorard, JE Gomborone, GW Libby, MJ Farthing - Gut, 1996 - gut.bmj.com
BACKGROUND: Patients with anxiety and depression often have bowel symptoms. Until
now, studies investigating a link between altered bowel habit and psychological illness have …

Initial response and subsequent course of Crohn's disease treated with elemental diet or prednisolone.

DA Gorard, JB Hunt, JJ Payne-James, KR Palmer… - Gut, 1993 - gut.bmj.com
Elemental diet is as effective as corticosteroids in the treatment of previously untreated
Crohn's disease. It is unclear whether a poor nutritional state is a prerequisite for efficacy of …

Escalating polypharmacy

DA Gorard - Journal of the Association of Physicians, 2006 - academic.oup.com
New drug treatments, new indications for older drug treatments, lower thresholds for treating
risk factors in preventative medicine, and an ageing population acquiring multiple …

Effect of a tricyclic antidepressant on small intestinal motility in health and diarrhea-predominant irritable bowel syndrome

DA Gorard, GW Libby, MJG Farthing - Digestive diseases and sciences, 1995 - Springer
Antidepressants are used in irritable bowel syndrome (IBS) and may have effects on the gut
independent of improving mood. We have investigated the actions of a tricyclic …

Pyogenic liver abscess

GJ Webb, TP Chapman, PJ Cadman… - Frontline …, 2014 - fg.bmj.com
Pyogenic liver abscess has a variable clinical presentation. Its management requires input
from several disciplines and is often coordinated by a gastroenterologist. This review …

Ambulatory small intestinal motility in'diarrhoea'predominant irritable bowel syndrome.

DA Gorard, GW Libby, MJ Farthing - Gut, 1994 - gut.bmj.com
Dysmotility of the duodenum and proximal jejunum has been reported in patients with
irritable bowel syndrome. This study extended these findings by recording fasting …

5-Hydroxytryptamine and human small intestinal motility: effect of inhibiting 5-hydroxytryptamine reuptake.

DA Gorard, GW Libby, MJ Farthing - Gut, 1994 - gut.bmj.com
Parenteral 5-hydroxytryptamine stimulates small intestinal motility, but the effect of
continuous stimulation with 5-hydroxytryptamine on the human migrating motor complex is …

Contrasting liver function test patterns in obstructive jaundice due to biliary structures and stones

JO Hayat, CJ Loew, KN Asrress, AS McIntyre… - Qjm, 2005 - academic.oup.com
Background: Obstructive jaundice is believed to be characterized by abnormalities of
alkaline phosphatase (ALP), rather than aspartate transaminase (AST). Aim: To compare …