Is dental health education effective? A systematic review of current evidence

EJ Kay, D Locker - Community dentistry and oral epidemiology, 1996 - Wiley Online Library
In order that health service resources are allocated in the way which most benefits the
population, systematic review of the available evidence regarding the effectiveness of …

Prevention. Part 8: The use of pit and fissure sealants in preventing caries in the permanent dentition of children

D Locker, A Jokovic, EJ Kay - British dental journal, 2003 - nature.com
This paper reviews evidence concerning the use of pit and fissure sealants in preventing
caries in the permanent dentition of children. While the evidence with respect to some …

Prevention. Part 7: professionally applied topical fluorides for caries prevention

R Hawkins, D Locker, J Noble, EJ Kay - British dental journal, 2003 - nature.com
This paper reviews the use of professionally applied topical fluorides (PATF) in caries
prevention. PATFs are indicated for children and adults with one or more decayed smooth …

[HTML][HTML] Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix

EJ Kay, K Paterson, C Riera-Domingo, D Sumpton… - Nature …, 2022 - nature.com
Elevated production of collagen-rich extracellular matrix is a hallmark of cancer-associated
fibroblasts (CAFs) and a central driver of cancer aggressiveness. Here we find that proline, a …

Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium

SE Reid, EJ Kay, LJ Neilson, AT Henze… - The EMBO …, 2017 - embopress.org
Tumor progression alters the composition and physical properties of the extracellular matrix.
Particularly, increased matrix stiffness has profound effects on tumor growth and metastasis …

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

P Altea-Manzano, G Doglioni, Y Liu, AM Cuadros… - Nature cancer, 2023 - nature.com
Metabolic rewiring is often considered an adaptive pressure limiting metastasis formation;
however, some nutrients available at distant organs may inherently promote metastatic …

Decision analysis of medical and surgical treatments for trigeminal neuralgia: how patient evaluations of benefits and risks affect the utility of treatment decisions

AL Spatz, JM Zakrzewska, EJ Kay - Pain, 2007 - Elsevier
Trigeminal neuralgia (TN) is a rare form of neuropathic facial pain characterised by severe,
paroxysmal pains in the face. Little is known about the decision process in treatment of TN …

The reasons for the extraction of various tooth types in Scotland: a 15-year follow up

LK McCaul, WMM Jenkins, EJ Kay - Journal of dentistry, 2001 - Elsevier
Objectives: The aim of this survey was to investigate the reasons for extraction of the various
tooth types in Scotland. This study replicated one which was undertaken 15 years earlier. A …

The reasons for extraction of permanent teeth in Scotland: a 15-year follow-up study

LK McCaul, WMM Jenkins, EJ Kay - British dental journal, 2001 - nature.com
Aims Although Scotland has the highest proportion of edentulous adults in the UK, the
frequency of edentulousness has fallen by 21% during the last 20 years. This study, carried …

Prevention. Part 4: Toothbrushing: what advice should be given to patients?

RM Davies, GM Davies, RP Ellwood, EJ Kay - British dental journal, 2003 - nature.com
This paper examines and summarises the evidence to support the advice that GDPs should
give their patients on toothbrushing. The strength of evidence is graded using a five-point …