The paper gives an overview on safe life and damage tolerance methods applied to railway
axles. It describes failure scenarios due to fatigue crack initiation and propagation. Besides …

Cell fusion techniques have been used to produce hybrids between myeloma cells and
antibody‐producing cells. The hybrid lines derived are permanently adapted to grow in …

Osteomyelitis is a serious bone infection typically caused by Staphylococcus aureus. The
pathogenesis of osteomyelitis remains poorly understood, mainly for lack of experimental …

Many clinical conditions including various types of cancers are complex and generally
require invasive, laborious, expensive and time-consuming investigations for their …

THE manufacture of predefined specific antibodies by means of permanent tissue culture
cell lines is of general interest. There are at present a considerable number of permanent …

Abstract lNTERLEUKIN-6 (IL-6) is a multifunctional cytokine that regulates various aspects of
the immune response, acute-phase reaction and haematopoiesis (for reviews see refs 1, 2) …

MURINE T-helper clones are classified into two distinct subsets (Thl and Th2) on the basis of
their patterns of lymphokine secretion. Thl clones secrete interleukin-2 (IL-2), tumour …

Effective and targeted conservation action requires detailed information about species, their
distribution, systematics and ecology as well as the distribution of threat processes which …

FUSION of myeloma cells which grow in tissue culture with spleen cells from an immunised
mouse provides a general method for obtaining cell lines (hybridomas) which make …

Background Inflammatory cytokines have been related to the development of adult
respiratory distress syndrome (ARDS), shock, and multiple organ dysfunction syndrome …