Dementia is arguably the most pressing public health challenge of our age. Since dementia
does not have a cure, identifying risk factors that can be controlled has become paramount …

Background Exposure to ambient air pollution increases morbidity and mortality, and is a
leading contributor to global disease burden. We explored spatial and temporal trends in …

Exposure to ambient air pollution is a major risk factor for global disease. Assessment of the
impacts of air pollution on population health and evaluation of trends relative to other major …

Air pollution is high on the global agenda and is widely recognised as a threat to both public
health and economic progress. The World Health Organization (WHO) estimates that 4.2 …

A small area study of cancer incidence in 1974–1986 was carried out to investigate an
unconfirmed report of a “cluster” of leukemias and lymphomas near the Sutton Coldfield …

Air pollution is a leading global disease risk factor. Tracking progress (eg, for Sustainable
Development Goals) requires accurate, spatially resolved, routinely updated exposure …

Objectives To compare the prevalence, clinical and radiographic characteristics of psoriatic
spondyloarthritis (PsSpA) in psoriatic arthritis (PsA), with ankylosing spondylitis (AS) …

Despite recent advances in the available statistical methods for geographical analysis, there
are many constraints to their application in environmental epidemiology. These include …

Air pollution is a major risk factor for global health, with 3 million deaths annually being
attributed to fine particulate matter ambient pollution (PM2. 5). The primary source of …

We develop scalable methods for fitting penalized regression spline based generalized
additive models with of the order of 104 coefficients to up to 108 data. Computational …