Direct electron transfer between copper-containing proteins and electrodes
The electrochemistry of some copper-containing proteins and enzymes, viz. azurin,
galactose oxidase, tyrosinase (catechol oxidase), and the “blue” multicopper oxidases …
galactose oxidase, tyrosinase (catechol oxidase), and the “blue” multicopper oxidases …
Free radical catalysis by galactose oxidase
JW Whittaker - Chemical Reviews, 2003 - ACS Publications
The copper metalloenzyme, galactose oxidase [EC 1.1. 3.9](GO), 1-3 is an efficient oxidation-
reduction catalyst utilizing an unusual free radical-coupled copper catalytic motif1, 4, 5 in its …
reduction catalyst utilizing an unusual free radical-coupled copper catalytic motif1, 4, 5 in its …
Structural biology of insulin and IGF1 receptors: implications for drug design
P De Meyts, J Whittaker - Nature reviews Drug discovery, 2002 - nature.com
Type 2 diabetes mellitus—in which the body produces insufficient amounts of insulin or the
insulin that is produced does not function properly to control blood glucose—is an …
insulin that is produced does not function properly to control blood glucose—is an …
Herbivory in global climate change research: direct effects of rising temperature on insect herbivores
JS Bale, GJ Masters, ID Hodkinson… - Global change …, 2002 - Wiley Online Library
This review examines the direct effects of climate change on insect herbivores. Temperature
is identified as the dominant abiotic factor directly affecting herbivorous insects. There is little …
is identified as the dominant abiotic factor directly affecting herbivorous insects. There is little …
Sideband cooling of micromechanical motion to the quantum ground state
The advent of laser cooling techniques revolutionized the study of many atomic-scale
systems, fuelling progress towards quantum computing with trapped ions and generating …
systems, fuelling progress towards quantum computing with trapped ions and generating …
[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts
KS Vimaleswaran, DJ Berry, C Lu, E Tikkanen… - PLoS …, 2013 - journals.plos.org
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …
public health concern. We explored the causality and direction of the relationship between …
[BOOK][B] Graphical models in applied multivariate statistics
J Whittaker - 2009 - dl.acm.org
The Wiley Paperback Series makes valuable content more accessible to a new generation
of statisticians, mathematicians and scientists. Graphical models--a subset of log-linear …
of statisticians, mathematicians and scientists. Graphical models--a subset of log-linear …
The support of human genetic evidence for approved drug indications
Over a quarter of drugs that enter clinical development fail because they are ineffective.
Growing insight into genes that influence human disease may affect how drug targets and …
Growing insight into genes that influence human disease may affect how drug targets and …
[BOOK][B] The child welfare challenge: Policy, practice, and research
Using both historical and contemporary contexts, The Child Welfare Challenge examines
major policy practice and research issues as they jointly shape child welfare practice and its …
major policy practice and research issues as they jointly shape child welfare practice and its …
[PDF][PDF] Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …