User profiles for "author:J Whittaker"

John Whittaker

- Verified email at mrc-bsu.cam.ac.uk - Cited by 22026

jb whittaker

- Verified email at lancaster.ac.uk - Cited by 9136

James Whittaker

- Verified email at uw.edu - Cited by 6546

Direct electron transfer between copper-containing proteins and electrodes

S Shleev, J Tkac, A Christenson, T Ruzgas… - Biosensors and …, 2005 - Elsevier
The electrochemistry of some copper-containing proteins and enzymes, viz. azurin,
galactose oxidase, tyrosinase (catechol oxidase), and the “blue” multicopper oxidases …

Free radical catalysis by galactose oxidase

JW Whittaker - Chemical Reviews, 2003 - ACS Publications
The copper metalloenzyme, galactose oxidase [EC 1.1. 3.9](GO), 1-3 is an efficient oxidation-
reduction catalyst utilizing an unusual free radical-coupled copper catalytic motif1, 4, 5 in its …

Structural biology of insulin and IGF1 receptors: implications for drug design

P De Meyts, J Whittaker - Nature reviews Drug discovery, 2002 - nature.com
Type 2 diabetes mellitus—in which the body produces insufficient amounts of insulin or the
insulin that is produced does not function properly to control blood glucose—is an …

Herbivory in global climate change research: direct effects of rising temperature on insect herbivores

JS Bale, GJ Masters, ID Hodkinson… - Global change …, 2002 - Wiley Online Library
This review examines the direct effects of climate change on insect herbivores. Temperature
is identified as the dominant abiotic factor directly affecting herbivorous insects. There is little …

Sideband cooling of micromechanical motion to the quantum ground state

JD Teufel, T Donner, D Li, JW Harlow, MS Allman… - Nature, 2011 - nature.com
The advent of laser cooling techniques revolutionized the study of many atomic-scale
systems, fuelling progress towards quantum computing with trapped ions and generating …

[HTML][HTML] Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

KS Vimaleswaran, DJ Berry, C Lu, E Tikkanen… - PLoS …, 2013 - journals.plos.org
Background Obesity is associated with vitamin D deficiency, and both are areas of active
public health concern. We explored the causality and direction of the relationship between …

[BOOK][B] Graphical models in applied multivariate statistics

J Whittaker - 2009 - dl.acm.org
The Wiley Paperback Series makes valuable content more accessible to a new generation
of statisticians, mathematicians and scientists. Graphical models--a subset of log-linear …

The support of human genetic evidence for approved drug indications

MR Nelson, H Tipney, JL Painter, J Shen, P Nicoletti… - Nature …, 2015 - nature.com
Over a quarter of drugs that enter clinical development fail because they are ineffective.
Growing insight into genes that influence human disease may affect how drug targets and …

[BOOK][B] The child welfare challenge: Policy, practice, and research

PJ Pecora, JK Whittaker, RP Barth, S Borja… - 2018 - taylorfrancis.com
Using both historical and contemporary contexts, The Child Welfare Challenge examines
major policy practice and research issues as they jointly shape child welfare practice and its …

[PDF][PDF] Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

…, FW Asselbergs, N Sattar, DA Lawlor, J Whittaker… - Bmj, 2014 - bmj.com
Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …