Purpose Neoadjuvant chemotherapy is established in the management of most resectable
esophageal and esophagogastric junction adenocarcinomas. However, assessing the …

Importance The prognostic role of the extent of lymphadenectomy during surgery for
esophageal cancer is uncertain and requires clarification. Objective To clarify whether the …

Importance Ninety-day mortality rates after esophagectomy are an indicator of the quality of
surgical oncologic management. Accurate risk prediction based on large data sets may aid …

Background There is increasing evidence for the use of exercise in cancer patients and data
supporting enhanced tumour volume reduction following chemotherapy in animal models …

Background & Aims Most patients with esophageal adenocarcinoma (EAC) present with de
novo tumors. Although this could be due to inadequate screening strategies, the precise …

Background & Aims Esophageal adenocarcinomas (EACs) are heterogeneous and often
preceded by Barrett's esophagus (BE). Many genomic changes have been associated with …

Background: Psychological distress is common among patients with oesophageal cancer.
However, little is known about the course and predictors of psychological distress among …

Background Early cancer recurrence after oesophagectomy is a common problem, with an
incidence of 20–30 per cent despite the widespread use of neoadjuvant treatment …

Cancers occurring at the gastroesophageal junction (GEJ) are classified as predominantly
esophageal or gastric, which is often difficult to decipher. We hypothesized that the …

Background: observational research is increasingly important in clinical decision-making.
Opt-out consent has been proposed as a more practical way to obtain participants' consent …