Background The aim of this study is to review accelerometer wear methods and correlations
between accelerometry and physical activity questionnaire data, depending on participant …

BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal
cancer. Identifying the genetic loci associated with colorectal tumor formation could …

Genetic and environmental risk factors and their interactions contribute to the development
of complex diseases. In this review, we discuss methodological issues involved in …

Purpose: To investigate the proportion of breast cancers arising in patients with germ line
BRCA1 and BRCA2 mutations expressing basal markers and developing predictive tests for …

Breast cancer is the most common cancer among women. Common variants at 27 loci have
been identified as associated with susceptibility to breast cancer, and these account for∼ …

Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Background: Colonoscopy with detection and removal of adenomas is considered a
powerful tool to reduce colorectal cancer (CRC) incidence. However, the degree of …

Age at menarche is a marker of timing of puberty in females. It varies widely between
individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes …

Microsatellite instability determines whether patients with gastrointestinal cancer respond
exceptionally well to immunotherapy. However, in clinical practice, not every patient is tested …

Background: We have previously demonstrated that breast cancers associated with
inherited BRCA1 and BRCA2 gene mutations differ from each other in their histopathologic …