Wound healing, as a normal biological process in the human body, is achieved through four
precisely and highly programmed phases: hemostasis, inflammation, proliferation, and …

The macrophage is a prominent inflammatory cell in wounds, but its role in healing remains
incompletely understood. Macrophages have many functions in wounds, including host …

Impaired wound healing in the elderly presents a major clinical and economic problem. With
the aging population growing in both number and percentage, the importance of …

Objectives To describe new WHO 2020 guidelines on physical activity and sedentary
behaviour. Methods The guidelines were developed in accordance with WHO protocols. An …

Angiogenic factors produced by monocytes-macrophages are involved in the pathogenesis
of chronic inflammatory disorders characterized by persistent angiogenesis. The possibility …

Insulin resistance is a major factor in the pathogenesis of type 2 diabetes in the elderly. To
investigate how insulin resistance arises, we studied healthy, lean, elderly and young …

Recent muscle biopsy studies have shown a relation between intramuscular lipid content
and insulin resistance. The aim of this study was to test this relation in humans by using a …

Angiogenesis is an essential component of normal wound repair, yet the primary mediators
of wound angiogenesis have not been well described. The current study characterizes the …

Clinical trials of small interfering RNA (siRNA) targeting vascular endothelial growth factor-A
(VEGFA) or its receptor VEGFR1 (also called FLT1), in patients with blinding choroidal …

The infiltration of neutrophils into injured tissue is known to protect wounds from invading
pathogens. However, more recent studies suggest that neutrophils might inhibit the wound …