Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

It is commonly held that the respiratory system has ample capacity relative to the demand for
maximal O2 and CO2 transport in healthy humans exercising near sea level. However, this …

Background: Prognosis in chronic obstructive pulmonary disease (COPD) is poorly
predicted by indices of air flow obstruction, because other factors that reflect the systemic …

This European Respiratory Society (ERS) statement provides a comprehensive overview on
physical activity in patients with chronic obstructive pulmonary disease (COPD). A …

Importance Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD)
requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to …

Summary Background The COPD Assessment Test (CAT) is responsive to change in
patients with chronic obstructive pulmonary disease (COPD). However, the minimum …

Background Age-related loss of muscle, sarcopenia, is recognised as a clinical syndrome
with multiple contributing factors. International European Working Group on Sarcopenia in …

Background The COPD (chronic obstructive pulmonary disease) assessment test (CAT) is a
recently introduced, simple to use patient-completed quality of life instrument that contains …

Background The relationship between physical activity, disease severity, health status and
prognosis in patients with COPD has not been systematically assessed. Our aim was to …